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A 3D Molecular Design model of Aquaporin

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Student handouts for use with the purple translation mat in the Flow of Genetic Information Kit ©

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Students can model different conditions and then predict which way water will move, making vocabulary like hypertonic, hypotonic, and isotonic more memorable. This is a kit you will use over and over as your curriculum progresses to deepen student understanding.

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A 3D Molecular Design Interactable about Monomers and Polymers

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https://3dmd.3dmoleculardesigns.com/hubfs/VideoScreenshots/ComparingPhospholipidMonolayersMicellesAndBilayers_1.png

A 3D Molecular Design short content video about monolayers, micelles, and bilayers.

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https://3dmd.3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/ArticulateScreenshots/waterMonomerToPolymer_1.jpg
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https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/SideChainExplorerAR_3.png

AR enhancements of the Amino Acid Starter Kit allow for the exploration of how sidechain properties drive protein folding

https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/SideChainExplorerAR_1.png
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Part 1 of 3D Molecular Designs Side Chain Interactable

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https://3dmd.3dmoleculardesigns.com/hubfs/VideoScreenshots/ComparingPurinesAndPyrimidines_1.png

A 3D Molecular Design short content video nvestigating purines and pyrimidines

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https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/WaterKitResourcesTeacherGuide_1.png

Considered the gateway kit for students to develop model literacy, this is a great beginning-of-the-year activity.

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https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/ChromosomeConnectionsKitResourcesStudentHandout_1.png

Conceptual understanding skyrockets as you invite students to investigate chromosomes at the microscopic and molecular scales! You will love the versatility of this kit as you explore the cell cycle, cell division, and genetics.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/ChromosomeConnectionsKitResourcesTeacherHandout_1.png
https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/BiotechnologyKitResourcesStudentHandout_1.png
  • Simulate PCR using flanking primers result to copy sequences of interest
  • Investigate how restriction endonucleases are used in DNA cloning
  • Explore the Sanger DNA sequencing method using chain-terminating fluorescent dideoxy nucleotide analogs
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https://3dmd.3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/VideoScreenshots/DMH_Video_Intro_States%20of%20Matter.jpg

A 3D Molecular Design short content video about modeling the states of matter

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https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/AminoAcidStarterKitResourcesTeacherGuide_1.png

As your students begin to realize that DNA is code for an amino acid sequence that ultimately determines protein structure, their confidence soars!

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https://3dmd.3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/VideoScreenshots/DMH_Video_Intro_Building%20a%20Phospholipid.jpg

A 3D Molecular Design short content video about the structure of phospholipids

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https://3dmd.3dmoleculardesigns.com/hubfs/Exploratorium%20Screenshots/ZincFingerExploritorium.png
A Jmol exploration of the 1ZAA Zinc Finger motif, complete with the amino acid sequence.
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3D Molecular Designs Anabolic Interactable

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https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/ChromosomeConnectionsKitResourcesStudentHandout_1.png

Conceptual understanding skyrockets as you invite students to investigate chromosomes at the microscopic and molecular scales! You will love the versatility of this kit as you explore the cell cycle, cell division, and genetics.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/ChromosomeConnectionsKitResourcesTeacherHandout_1.png
https://3dmoleculardesigns.com/hubfs/Screenshot%202025-02-26%20123302.png

In this introductory lesson, students explore hydrogen and covalent bonds within and between molecules. Working through this independent activity with their physical models, lab notebook, and several different molecular representations of water, they learn about polarity and will model cohesion and hydrogen bonding.

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A 3D Molecular Design Interactable about Binding Chemicals

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https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/TransferringModelsWithTheFlowOfGeneticInformationKitAR_1.png

AR enhancements of DNA show the similarities and differences between multiple DNA representations

https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/ProteinTranlsationWithTheFlowOfGeneticInformationKitAR_2.png
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A 3D Molecular Design Interactable about Shapes and their binding properties

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Fun, self-correcting, and intuitive, this kit results in confidence and learning that lasts for years.

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As your students begin to realize that DNA is code for an amino acid sequence that ultimately determines protein structure, their confidence soars!

https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/TransferringModelsWithTheDynamicDNAKitAR_3.png

AR enhancements of DNA show the similarities and differences between multiple DNA representations

https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/TransferringModelsWithTheDynamicDNAKitAR_2.png
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Students will create a model of a protein based on the 3D coordinates displayed on a webpage.

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This hands-on modeling kit is designed to help students visualize protein structures and how a protein's unique shape impacts its function.

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Students will explore protein structures on web pages to identify similarities and differences.

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A 3D Molecular Design video about the Solubility of Alcohols

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A 3D Molecular Design short content video about triglyceride structure, oils, and fats

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The 3DMD Jmol Training Guide covers how to access Jmol, design a protein model, and export it for 3D printing.

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Set your students up for successful CRISPR investigations by first exploring how bacteria seek and destroy viral invaders.

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Set your students up for successful CRISPR investigations by first exploring how bacteria seek and destroy viral invaders.

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Students explore the properties of amino acids and how they are connected to form a polypeptide.

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Students will learn about alpha helices and beta sheets and how they are displayed in molecular visualization software.

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Students will explore how the properties of the amino acid sidechains influence the tertiary structure of a protein.

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AR enhancements of the Water kit allow students to explore and model the states of matter

https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/ExploringStatesofMatterAR_1.png
https://3dmd.3dmoleculardesigns.com/hubfs/VideoScreenshots/ComponentsOfAPhospholipid_1.png

A 3D Molecular Design short content video about the diversity of phospholipids

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https://3dmd.3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/TeacherStudentGuideScreenshots/NeuromuscularSynapsePosterColoringPage.png
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Part 2 of 3D Molecular Designs Side Chain Interactable

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A 3D Molecular Design Interactable about Catabolic reactions

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Free resources to use with your class as they begin to explore our AR app, available in both the Apple and Google Play stores.
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Tim Herman, PhD, 3D Molecular Designs' founder and scientific officer, explores the CRISPR/Cas9 system.

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https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/ProteinTranlsationWithTheFlowOfGeneticInformationKitAR_2.png

AR enhancements of the Flow of Genetic Information Kit allow students to model protein synthesis and investigate how different antibiotics inhibit protein production

https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/ProteinTranlsationWithTheFlowOfGeneticInformationKitAR_1.png
https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/FlowofGeneticInformationKitResourcesStudentGuide_1.png

A 3D Molecular Design video demonstrating the Flow of Genetic Information kit

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https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/DiscoveringPolarityAR_1.png

AR enhancements of the Water Kit allow students to discover the molecular reason for water polarity

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https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/FoldingRealProteinsZincFingersAR_2.png

AR enhancements of the Amino Acid Starter Kit allow students to begin investigating the different levels of protein folding

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Dr. Goodsell creates cellular landscapes that accurately illustrate the size, shape, and distribution of proteins in a B-cell

https://3dmd.3dmoleculardesigns.com/hubfs/Exploratorium%20Screenshots/MoleculeMakerImage.png

Load an existing SMILE file or build your own small molecules. Export them as images for use in a document or presentation or export them as .STL files for 3D Printing

https://3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/Digital%20Modeling%20Hub%20Images/physical%20chemical%20props%20of%20water.jpg

Considered the gateway kit for students to develop model literacy, this is a great beginning-of-the-year activity.

https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/ExtendingTheDNADoubleHelixWithDynamicDNAKitAR_3.png

AR enhancements of the Dynamic DNA kit allow students to begin investigating DNA - protein interactions

https://3dmd.3dmoleculardesigns.com/hubfs/AugmentedRealityScreenshots/ExtendingTheDNADoubleHelixWithDynamicDNAKitAR_2.png
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https://3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/Digital%20Modeling%20Hub%20Images/Screenshot%202025-01-23%20143429.png

Webinar Series:

CRISPR Cas-9 - A Powerful New Tool for Editing the Human Genome

CRISPR Innovations: Clever and Cleverer

Tim Herman, PhD - 3D Molecular Designs

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/EnzymesInActionKitResourcesStudent_1.png

Excellent at revealing student thinking, this kit can complement traditional classroom assignments like the catalase or amylase labs,

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/EnzymesInActionKitResourcesStudent_2.png
https://3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/Digital%20Modeling%20Hub%20Images/Screenshot%202025-02-07%20133722.png

Tim Herman, PhD, 3D Molecular Designs' founder and scientific officer, explores the CRISPR/Cas9 system.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/WaterKitResourcesTeacherGuide_1.png

Considered the gateway kit for students to develop model literacy, this is a great beginning-of-the-year activity.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/WaterKitResourcesStudentGuide_1.png
https://3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/Screenshot%202025-01-22%20093858.png
https://3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/Digital%20Modeling%20Hub%20Videos/PMTK_parfitt.png
https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/InsulinmRNAToProteinKitStudentHandout_1.png

Your students can connect protein synthesis to blood sugar regulation as they fold their own insulin model.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/InsulinmRNAToProteinKitStudentHandout_2.png
https://3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/Digital%20Modeling%20Hub%20Images/Screenshot%202025-02-04%20150233.png
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https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/NaCLLatticeStudentHandout_1.png

Keep this mesmerizing model on your desk to invite student questions


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https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/DNAStarterKitResourcesTeacherHandout_1.png

This easy-to-build model is a perfect starting point that students can use to test their ideas and transfer their understanding to other, more complex models.


https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/DNAStarterKitResourcesTeacherHandout_2.png
https://3dmd.3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/VideoScreenshots/DMH_Video_Intro_RNA%20Processing%20(1).jpg

A 3D Molecular Design short content video about RNA processing, including polyadenylation, methyl caps, and more.

https://shop.3dmoleculardesigns.com/cdn/shop/files/INSFK_A_S4_Web.jpg

Your students can connect protein synthesis to blood sugar regulation as they fold their own insulin model.

https://3dmd.3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/VideoScreenshots/DMH_Video%20Intro_Chromosome%20and%20Gene%20Structures.jpg

A 3D Molecular Design short content video about chromosome structure.

https://3dmd.3dmoleculardesigns.com/hubfs/Exploratorium%20Screenshots/JUDEImage.png

A molecular structure file includes the X, Y, and Z coordinates to position each atom in a molecule in 3D space. The buttons below will load structure files in the Jmol window to the right.

https://shop.3dmoleculardesigns.com/cdn/shop/files/BTK_Seq_glamor2.jpg

Amplify understanding as students model the molecular processes in your pGLO or crime scene labs.

https://3dmd.3dmoleculardesigns.com/hubfs/Exploratorium%20Screenshots/ProteinExploritorium_1.png
A Jmol exploration of any PDB file you choose, complete with amino acid sequence.
https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/DynamicDNAKitResourcesStudentGuide_1.png

Thanks to our patented design innovations, the structure of this molecule is revealed to students through their own investigation.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/DynamicDNAKitResourcesTeacherGuide_1.png
https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/TourOfAHumanCellTeacherGuides_1.png

Dr. Goodsell creates cellular landscapes that accurately illustrate the size, shape, and distribution of proteins in a B-cell

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/TourOfAHumanCellTeacherGuides_2.png
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Learn how to prepare your Modeling Tie to create an accurate model of a protein.

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Learn how to fold your Modeling Tie into an accurate model of a protein.

https://3dmd.3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/VideoScreenshots/DMH_Video_Intro_ID%20Regions%20Chromosome.jpg

A 3D Molecular Design short content video about p arms, q arms, telomeres and more

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https://shop.3dmoleculardesigns.com/cdn/shop/files/SCK1_glamor.jpg

Your students will uncover how electrical and chemical signals allow us to move, breathe, and think, then predict what happens when things go wrong.

https://learn.3dmoleculardesigns.com/hubfs/Product%20Promo%20Photos/Chromosome%20Connections%20Kit/Chromosome%20Connections%20Kits%205.jpg

Conceptual understanding skyrockets as you invite students to investigate chromosomes at the microscopic and molecular scales! You will love the versatility of this kit as you explore the cell cycle, cell division, and genetics.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/NeuronModelingKitStudentHandout_1.png

Get your students' own neurons firing with these models.

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https://learn.3dmoleculardesigns.com/hubfs/Lending%20Library/Dynamic%20DNA%20Kit/DDNA_LL_glamour3_Web.jpg

Thanks to our patented design innovations, the structure of this molecule is revealed to students through their own investigation.

https://3dmd.3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/VideoScreenshots/DMH_Video_Intro_Exploring%20Saturated.jpg

A 3D Molecular Design Short Content video modeling different types of solutions

https://3dmd.3dmoleculardesigns.com/hubfs/Digital%20Modeling%20Hub/VideoScreenshots/Screenshot%20unsat%20sat%20supersat%201.png
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https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/MapOfTheHumanGlobinGeneTeacherHandout_1.png

You will astonish your students with how much information is in one gene just by unrolling this 15-foot map in the classroom.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/MapOfTheHumanGlobinGeneStudentHandout_1.png
https://3dmd.3dmoleculardesigns.com/hubfs/Screenshot%202024-10-16%20155507.png

Cytochrome C is an important protein structure involved in carrying electrons during respiration.

https://3dmd.3dmoleculardesigns.com/hubfs/Screenshot%202024-10-16%20155452.png

Immunoglobulin Folds are an important protein motif found immunology proteins such as antibodies. 

https://3dmd.3dmoleculardesigns.com/hubfs/Screenshot%202024-10-16%20155500.png

Zinc Fingers are an important family of protein structures involved in regulating access to DNA in the nucleus of our cells. 

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/SynapseContstructionKitStudentHandout_1.png

Puzzling promotes sensemaking when students engineer an enzyme's active site.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/SubstrateSpecificityKitStudentHandout_1.png
https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/SynapseContstructionKitTeacherHandout_1.png

Your students will uncover how electrical and chemical signals allow us to move, breathe, and think, then predict what happens when things go wrong.

https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/SynapseContstructionKitStudentHandout_1.png
https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/ModelingMiniTooberTeacherHandout_1.png
https://3dmd.3dmoleculardesigns.com/hubfs/TeacherStudentGuideScreenshots/ModelingMiniTooberTeacherHandout_1.png
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https://3dmoleculardesigns.com/hubfs/PSMP_A_P1_glamour_Web-1.jpg
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AR Training App Resources

Access: Available as a Free Resource
Link: See Student Handouts Below

Activity Type: Augmented Reality Activity


The 3DMD AR app allows students to further explore 3D Molecular Designs' kits and models through augmented reality-based activities. 3DMD AR uses physical models as AR targets and leads students through digital learning activities. As students progress through AR activities, they will continue to manipulate physical models, actively engaging in making sense of molecular processes through collaboration with classmates. Additional resources are available to help students learn to navigate the app.

Students can work in groups using the same set of models. Once one student has scanned and captured the model image, they can view it in 3D mode so others in their group can use the model. A student handout is included with this activity which helps provide scaffolding as students navigate the activity.

Augmented reality training modules allow students to model science concepts beyond the limitations of the physical models and learn how to use the 3DMD AR app. Physical models' sizes can be extended, atomic and molecular motion is shown, and models can be manipulated into 3d shapes. They are intended to be used with a physical kit and include application to real-world settings. These training activities have been designed for students to complete individually or with partners.

Become an Educator to get access to the answer keys!